
This month we are featuring our USA - Central Florida Life Science Cluster Ecosystem as our Ecosystem of the Month.
What is the approximate stakeholder breakdown of your ecosystem?
Our Cluster Initiative – Cenfluence has a unique stakeholder breakdown, supported by a combination of public, private, and research institutions. Cenfluence, is under the Florida High Tech Corridor and benefits from funding and backing from university systems such as the University of Central Florida and the University of South Florida, as well as local governments including Orange County, the City of Orlando, and Seminole County. Additionally, organizations like The Orlando Economic Partnership and Duke Energy are key partners. In total, there are more than 150 relevant stakeholders within our ecosystem that are utilized by our over 230 cluster members.
Cenfluence’s ecosystem also supports a robust workforce, with its cluster members generating over 15,000 full-time jobs and more than 2,700 part-time jobs. Notably, 40% of these businesses are women- or minority-owned, demonstrating Cenfluence’s commitment to fostering diversity and inclusion. Since its inception, Cenfluence has helped identify over $48.1 million in tailored business opportunities and secured $26.2 million in funding for its members. By leveraging partnerships with over 150 entrepreneurial support organizations across Central Florida, Cenfluence connects its members with resources for research and development, funding opportunities, and pathways to international markets. This ecosystem is designed to fuel business growth for high-tech companies, driving innovation and increasing global competitiveness.

Who are the top 3 champions from your Ecosystem?

What EU funding/collaboration are you involved with, or you would like to be part of?
Our Cluster Organization and our Cluster Members are interested in collaborating with like organizations under the Horizon Europe – Health Work Program.
Our Cluster Members have provided letters of support on Horizon Europe proposals under the Work Program Health. There are opportunities for our Cluster Members specialized in fields related to the six ‘destinations’ of the Work Program to participate as full partners as specified by the Program: “In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.”
What are the key priorities and themes for your ecosystem?
The themes for the Cenfluence ecosystem revolve around fostering innovation, leveraging partnerships, and enhancing regional strengths. Cenfluence focuses on creating internationally recognized industry clusters that are competitive on a global scale. This is achieved by supporting high-tech business growth, connecting members with research and development opportunities, and facilitating partnerships that integrate academia, government, and private industry. Cenfluence’s key priorities are the following:
This multi-faceted approach helps Cenfluence support over 230 members across diverse industry sectors.

What is your primary strength as an ecosystem?
Cenfluence’s primary strength lies in its collaborative ecosystem, known for playing well with various entities across Central Florida. Collaboration is key, as we bring together stakeholders from industry, academia, and government, spanning 23 counties.
This broad reach enables Cenfluence to assist European and local companies:

Which are the main hospitals in your ecosystem and which are the most active in your ecosystems?
The main hospitals in the Cenfluence ecosystem include AdventHealth, Orlando Health, Nemours Children’s Hospital, the Orlando VA Medical Center, HCA’s Central Florida Regional Hospital, Tampa General Hospital (TGH), Moffitt Cancer Center, and facilities within Lake Nona’s Medical City.
AdventHealth and Orlando Health are particularly active, with AdventHealth supporting cutting-edge research through initiatives like the Diabetes Institute and Orlando Health advancing healthcare through its UF Health Cancer Center. Additionally, Tampa General Hospital (TGH) and Moffitt Cancer Center are key players in the region, with TGH providing extensive trauma and transplant services, and Moffitt’s global leadership in cancer research and care.
A key development in this ecosystem is Lake Nona’s Medical City, which houses a concentrated cluster of medical institutions, research facilities, and cutting-edge healthcare companies. This includes UCF’s College of Medicine and the UCF Lake Nona Hospital, a joint venture with HCA Healthcare
This area, recognized as a global medical hub, not only strengthens Central Florida’s healthcare sector but also enhances its reputation as a center for medical innovation and research. The collaboration between hospitals, universities, and businesses within Lake Nona significantly contributes to the high-tech and life sciences ecosystem in the region.
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